Snoring causes damage and prevents healing in the upper airway tract

The recurrent vibrations caused by snoring can lead to injuries in the upper airways of people who snore heavily. This in turn, can cause swallowing dysfunction and render individuals more vulnerable for developing the severe condition obstructive sleep apnea. These findings are reported by researchers at Umeå University, Sweden. Their on-going research focuses on the processes behind vibratory damage and healing of the upper airway tract. The data generated will help identify people at high risk of developing sleep apnea and to find novel treatment strategies.

“Besides the disturbing effects, constant snoring can be a significant health risk. Nonetheless, there are indications that our research will guide towards early preventive measures and in the long term also enhance healing of damaged tissue caused by snoring,” says Associate Professor Per Stål, research leader at the Department of Integrative Medical Biology at Umeå University.

Researchers in Umeå have shown that snorers and sleep apnea patients have neuromuscular injuries in the upper respiratory tract. The injuries can be seen at both the structural and molecular level. Researchers could also observe a correlation between snoring and swallowing dysfunction as well as a relation between nerve damage and obstructive sleep apnea. Sleep apnea is characterized by repeated collapse of the upper respiratory tract leading to respiratory arrest during sleep, which increases the risk of cardiovascular disease.

The studies show that people who constantly snore heavily and have sleep apnea displayed a loss of nerves and muscle mass in the soft palate. Furthermore, the attempts by the body to heal damaged tissue were disturbed resulting in an abnormal muscle structure. Another interesting finding was that muscle fibers in the soft palate lacked or had a disturbed organization of certain structural proteins. These proteins stabilize the organelles of the muscle cell and support cellular structures related to energy production and muscle fibre contraction.

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